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. 2021 Jun;8(2):69-80.
doi: 10.1007/s40475-021-00227-4. Epub 2021 Jan 25.

Pediatric Cerebral Malaria

Affiliations

Pediatric Cerebral Malaria

Geoffrey Guenther et al. Curr Trop Med Rep. 2021 Jun.
No abstract available

Keywords: Africa; clinical trials; coma; malaria; vaccine.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: Geoffrey Guenther, Daniel Muller, Dominic Moyo, and Douglas Postels declare that they have no conflicts of interest

Figures

Figure 1:
Figure 1:
Brain MRI findings in children with cerebral malaria Panel A shows normal brain volume in a child with cerebral malaria. This sagittal T1 weighted sequence, obtained on a General Electric Signa Ovation 0.35 T scanner, has normal position of the cerebellar tonsils and normal width of the extra-axial fluid spaces including the pre-pontine space. Panel B, obtained from the same patient, is an axial T2 weighted image at the level of the basal ganglia demonstrating normal sulcal outlines with no effacement and normal grey-white matter differentiation. Panel C shows highly increased brain volume in a child with cerebral malaria. This coronal T2 weighted image at the level of the occipital horns of the lateral ventricles demonstrates markedly increased brain volume with generalized sulcal effacement and reduced differentiation of grey and white matter. Panel D, obtained from the same patient, demonstrates sulcal effacement, multifocal areas of reduced grey-white matter differentiation, and partial effacement of the lateral ventricles.

References

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