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. 2021 Jun 18;14(6):881-886.
doi: 10.18240/ijo.2021.06.14. eCollection 2021.

Evaluation of macular vessel density changes after vitrectomy with silicone oil tamponade in patients with rhegmatogenous retinal detachment

Jian Jiang  1   2   3 , Song Chen  1   2 , Ya-Ding Jia  3 , Rui Li  3 , Jin-Xiu Zhou  3 , Rui-Mei Li  3
Affiliations

Evaluation of macular vessel density changes after vitrectomy with silicone oil tamponade in patients with rhegmatogenous retinal detachment

Jian Jiang et al. Int J Ophthalmol. .

Abstract

Aim: To evaluate macular microvasculature changes in eyes after pars plana vitrectomy (PPV) and intraocular silicone oil (SO) tamponade for macula-off rhegmatogenous retinal detachment (RRD) using optical coherence tomography angiography (OCTA).

Methods: Totally 19 eyes (19 patients) with macula-off RRD who underwent PPV and intraocular SO tamponade were retrospectively reviewed. The parafoveal superficial capillary plexus (SCP) vessel density (VD), deep capillary plexus (DCP) VD, choriocapillaris plexus (CCP) VD, and foveal macular thickness were evaluated using OCTA throughout 16wk postoperatively. The values of healthy fellow eyes were used as control.

Results: The parafoveal SCP, DCP, and CCP VDs were significant increased over time in RRD eyes during the 12wk postoperatively, then decreased at 16wk postoperatively (all P<0.01). The ratios of RRD eyes and fellow healthy eyes (r/f ratios) of the SCP and DCP VDs were lower than those of the CCP VD postoperatively (all P<0.05). There were not significant differences in the r/f ratios between SCP and DCP VDs postoperatively (all P>0.05).

Conclusion: The parafoveal SCP, DCP, and CCP VDs gradually recover over time after PPV surgery with SO tamponade. Long-time SO tamponade might decrease postoperative macular VDs. Compared to parafoveal CCP VD, the parafoveal SCP and DCP VDs were more vulnerable in RRD eyes postoperatively.

Keywords: optical coherence tomography angiography; rhegmatogenous retinal detachment; silicone oil; vessel density; vitrectomy.

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Figures

Figure 1
Figure 1. Optical coherence tomography angiography images of a 35-year-old male patient with macula-off RRD showing superficial capillary plexus (SCP) and deep capillary plexus (DCP) of the RRD eye at week 12 postoperatively
A: Measurements for SCP vessel density (VD): OCTA en-face image and B-scan image (red line: internal limiting membrane; green line: inner plexiform layer); B: Measurements for DCP VD: OCTA en-face image and B-scan image (green line: inner plexiform layer; red line: outer plexiform layer).
Figure 2
Figure 2. Optical coherence tomography angiography images of a 35-year-old male patient with macula-off RRD showing choriocapillaris plexus (CCP) of the RRD eye at week 12 postoperatively
A: Radius of yellow circle is 1.5 mm; B: Radius of yellow circle is 0.5 mm. The parafoveal flow area=flow area of A yellow circle−flow area of B yellow circle. The parafoveal area=selected area of A yellow circle−selected area of B yellow circle. CCP VD=parafoveal flow area/parafoveal area.
Figure 3
Figure 3. The curve of mean r/f ratio of parafoveal VDs
The mean r/f ratios of the parafoveal SCP, DCP, and CCP VDs increased within 12wk postoperatively, then decreased at the 16wk postoperatively.
See this image and copyright information in PMC

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