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Editorial
. 2021 Sep;65(3):241-242.
doi: 10.1165/rcmb.2021-0227ED.

Toward a More Precise Solution to Asthma Therapy

Katrina E Traber  1 , David M Center  1
Affiliations
Editorial

Toward a More Precise Solution to Asthma Therapy

Katrina E Traber et al. Am J Respir Cell Mol Biol. 2021 Sep.
No abstract available

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Figures

Figure 1.
Figure 1.
Stimulation of interstitial macrophages by IL33 leads to activation and polarization toward an M2 phenotype. IL33-activated macrophages then stimulate ILC2s to produce the type 2 cytokines IL5 and IL13. Treatment of IL33-activated IMs with R848 drives their polarization away from M2 and induces the production of IL27, which inhibits ILC2 production of type 2 cytokines. Figure created with BioRender.com. ILC2 = type 2 innate lymphocyte; IM = interstitial macrophage; M2 = macrophage type 2.
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References

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