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Review
. 2021 Aug:224:153384.
doi: 10.1016/j.prp.2021.153384. Epub 2021 Feb 16.

Covid19, beyond just the lungs: A review of multisystemic involvement by Covid19

Anam Singh  1 , Sufian Zaheer  2 , Naveen Kumar  3 , Tanisha Singla  4 , Sunil Ranga  5
Affiliations
Review

Covid19, beyond just the lungs: A review of multisystemic involvement by Covid19

Anam Singh et al. Pathol Res Pract. 2021 Aug.

Abstract

With the commencement of the COVID19 pandemic, following its 1st case reported in Wuhan in China, the knowledge about the virus as well as the symptoms produced by the disease have drastically increased to this day. The manifestations of COVID19 is now known to affect multiple organ systems of the body, which have shown to have acute as well as chronic complications. Histopathological analysis of the biopsies from the affected organs have implied a direct cytopathic effect of the virus but at the same time not ruling out other causes like hypoxia metabolic changes etc., occurring during the course of the disease. In this review article, we have highlighted the histopathological changes in various organs as reported by various studies throughout the world for a better understanding of the etiopathogenesis of COVID19.

Keywords: COVID19; Diffuse alveolar damage; Lungs; Multi-systemic.

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Figures

Fig. 1
Fig. 1
Diagrammatic picture showing the multisystemic involvement of COVID19 and enumerating the commonly observed histo-pathological changes in each affected organ.
See this image and copyright information in PMC

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