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Comment
. 2021 Jun 29;12(3):e0143321.
doi: 10.1128/mBio.01433-21. Epub 2021 Jun 22.

Studies on the Regulation of Arginine Metabolism in Cyanobacteria Should Include Mixotrophic Conditions

Enrique Flores  1
Affiliations
Comment

Studies on the Regulation of Arginine Metabolism in Cyanobacteria Should Include Mixotrophic Conditions

Enrique Flores. mBio. .
No abstract available

Keywords: arginine biosynthesis; arginine catabolism; mixotrophy; ornithine-ammonium cycle.

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Figures

FIG 1
FIG 1
Schematic of arginine metabolism and some adjacent pathways in cyanobacteria. Arginine biosynthesis flux is shown in blue and arginine catabolism in garnet color. The upper part shows the GS/GOGAT pathway that produces the arginine precursor, glutamate, and the lower part shows arginine destinies other than protein synthesis, i.e., cyanophycin and polyamine synthesis. The regulatory network of NAGK is shown emphasizing functionality rather than molecular detail (i.e., NAGK-PII-ATP or PII-PirA complex formation is not indicated). For clarity, not all reactants, products, and stoichiometries are detailed, but places of energy input in the form of ATP are noted. Abbreviations: AgrE, arginine-guanidine-removing enzyme that carries sequential arginine dihydrolase and ornithine cyclodeaminase activities; Arg-Suc, argininosuccinate; ASS, argininosuccinate synthase; BgtBA, ABC transporter for basic amino acids and glutamine; Cit, citrulline; GS, glutamine synthetase; GOGAT, glutamine-2-oxoglutarate aminotransferase; [H], reducing power; 2OG, 2-oxoglutarate; Orn, ornithine; PII, glnB gene product; PirA, PII-interacting regulator of arginine synthesis; PutA, bifunctional proline oxidase that carries sequential proline dehydrogenase and glutamate-semialdehyde dehydrogenase activities.
See this image and copyright information in PMC

Comment on

References

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