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. 2021 Oct;259(10):3019-3026.
doi: 10.1007/s00417-021-05244-7. Epub 2021 Jun 22.

Gonioscopy-assisted transluminal trabeculotomy in primary angle-closure glaucoma

Eamon Sharkawi  1 , Paul H Artes  2   3 , Daniel Josef Lindegger  4 , Maria Laura Dari  5 , Mohamad El Wardani  6 , Jérôme Pasquier  7 , Adriano Guarnieri  5
Affiliations

Gonioscopy-assisted transluminal trabeculotomy in primary angle-closure glaucoma

Eamon Sharkawi et al. Graefes Arch Clin Exp Ophthalmol. 2021 Oct.

Abstract

Purpose: This study aims to report on outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in eyes with primary angle-closure glaucoma (PACG).

Methods: This study is a prospective, interventional, non-comparative case series. A total of 103 eyes from 88 patients with PACG underwent an ab interno trabeculotomy, using either a 5.0 polypropylene suture or an illuminated microcatheter, with up to 24 months of follow-up. The main outcome measures were intraocular pressure (IOP), number of antiglaucoma medications, success rate (IOP reduction ≥ 20% from baseline or IOP between 6 and 21 mmHg, without further glaucoma surgery) and complication rate.

Results: The mean preoperative IOP was 21.4 (SD 7.4) mmHg using 2.5 (SD 1.1) glaucoma medications. These decreased postoperatively to 12.1 (SD 2.4) mmHg and 0.8 (SD 1.2) medications, at 24 months (P < 0.05). Success rate was 78% at 24 months of follow-up, and complication rate was 4.8%.

Conclusion: At 24 months of follow-up, our results for GATT in PACG demonstrate that this procedure effectively lowers IOP in this subtype of glaucoma, with a low complication rate.

Keywords: Angle closure; GATT; Gonioscopy-assisted transluminal trabeculotomy; MIGS; Minimally invasive glaucoma surgery.

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References

    1. Sun X, Dai Y, Chen Y et al (2017) Primary angle closure glaucoma: what we know and what we don’t know. Prog Retin Eye Res 57:26–45 - DOI
    1. Friedman DS, Foster PJ, Aung T, He M (2012) Angle closure and angle-closure glaucoma: what we are doing now and what we will be doing in the future. Clin Exp Ophthalmol 40:381–387 - DOI
    1. Wright C, Tawfik MA, Waisbourd M, Katz LJ (2016) Primary angle-closure glaucoma: an update. Acta Ophthalmol 94:217–225 - DOI
    1. Beasley H, Fraunfelder FT (1979) Retinal detachments and topical ocular miotics. Ophthalmology 86:95–98. https://doi.org/10.1016/S0161-6420(79)35529-4 - DOI - PubMed
    1. Pape LG, Forbes M (1978) Retinal detachment and miotic therapy. Am J Ophthalmol 85:558–566. https://doi.org/10.1016/S0002-9394(14)75255-9 - DOI - PubMed

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