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Editorial
. 2021 Jun;10(3):364-366.
doi: 10.21037/hbsn-21-144.

Comment on " Hypothermic machine perfusion in liver transplantation-a randomized trial"

Fabien Robin  1   2 , Heithem Jeddou  1
Affiliations
Editorial

Comment on " Hypothermic machine perfusion in liver transplantation-a randomized trial"

Fabien Robin et al. Hepatobiliary Surg Nutr. 2021 Jun.
No abstract available

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Conflict of interest statement

Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/hbsn-21-144). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Diagram of the procedural steps in the procurement of DCD donors. The left side shows the procedure performed in the trial and the right side shows the procedure performed in France. DCD, donors after cardiac death; NRP, normothermic regional perfusion.
See this image and copyright information in PMC

Comment on

  • Hypothermic Machine Perfusion in Liver Transplantation - A Randomized Trial.
    van Rijn R, Schurink IJ, de Vries Y, van den Berg AP, Cortes Cerisuelo M, Darwish Murad S, Erdmann JI, Gilbo N, de Haas RJ, Heaton N, van Hoek B, Huurman VAL, Jochmans I, van Leeuwen OB, de Meijer VE, Monbaliu D, Polak WG, Slangen JJG, Troisi RI, Vanlander A, de Jonge J, Porte RJ; DHOPE-DCD Trial Investigators. van Rijn R, et al. N Engl J Med. 2021 Apr 15;384(15):1391-1401. doi: 10.1056/NEJMoa2031532. Epub 2021 Feb 24. N Engl J Med. 2021. PMID: 33626248 Clinical Trial.

References

    1. van Rijn R, Schurink IJ, de Vries Y, et al. Hypothermic machine perfusion in liver transplantation—a randomized trial. N Engl J Med 2021;384:1391-401. 10.1056/NEJMoa2031532 - DOI - PubMed
    1. Guarrera JV, Henry SD, Samstein B, et al. Hypothermic machine preservation in human liver transplantation: the first clinical series. Am J Transplant 2010;10:372-81. 10.1111/j.1600-6143.2009.02932.x - DOI - PubMed
    1. Nasralla D, Coussios CC, Mergental H, et al. A randomized trial of normothermic preservation in liver transplantation. Nature 2018;557:50-6. 10.1038/s41586-018-0047-9 - DOI - PubMed
    1. Muller X, Mohkam K, Mueller M, et al. Hypothermic oxygenated perfusion versus normothermic regional perfusion in liver transplantation from controlled donation after circulatory death: first international comparative study. Ann Surg 2020;272:751-8. 10.1097/SLA.0000000000004268 - DOI - PubMed
    1. Watson CJE, Hunt F, Messer S, et al. In situ normothermic perfusion of livers in controlled circulatory death donation may prevent ischemic cholangiopathy and improve graft survival. Am J Transplant 2019;19:1745-58. 10.1111/ajt.15241 - DOI - PubMed