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Comment
. 2021 Sep;83(3):381-412.
doi: 10.1016/j.jinf.2021.06.017. Epub 2021 Jun 20.

Waning antibodies in SARS-CoV-2 naïve vaccinees: Results of a three-month interim analysis of ongoing immunogenicity and efficacy surveillance of the mRNA-1273 vaccine in healthcare workers

Marie Tré-Hardy  1 , Roberto Cupaiolo  2 , Alain Wilmet  2 , Ingrid Beukinga  2 , Laurent Blairon  2
Affiliations
Comment

Waning antibodies in SARS-CoV-2 naïve vaccinees: Results of a three-month interim analysis of ongoing immunogenicity and efficacy surveillance of the mRNA-1273 vaccine in healthcare workers

Marie Tré-Hardy et al. J Infect. 2021 Sep.
No abstract available

Keywords: Covid-19; Efficacy; Immunogenicity; SARS-CoV-2; mRNA-1273 vaccine.

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Conflict of interest statement

Conflicts of Competing Interest The authors have no relevant competing interest to disclose in relation to this work.

Figures

Fig 1
Fig. 1
Antibody responses in seronegative (A) and seropositive (B) HCWs after mRNA-1273 vaccination. It shows the titers of SARS-CoV-2 IgG antibodies directed against the subunits (S1) and (S2) of the virus spike protein before (T0), 2 weeks after the first injection (T1), 2 weeks after the second injection (T2) and 3 months after the first infection (T3) according to the participant serological status (n = 205). The Box-and-Whisker plot represents the 25th and 75th percentiles. Inside the box, the horizontal line indicates the median (the 50th percentile). Discs in light grey represent far out values. A Wilcoxon test was used to assess the changes in IgG levels between T0, T1, T2 and T3 times within seronegative (n = 161) and seropositive subjects (n = 44). A P-value < 0.05 was considered significant.
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