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Review
. 2021 Jun 18;11(6):180-186.
doi: 10.5500/wjt.v11.i6.180.

Hypertension and obesity in living kidney donors

Mahmoud M Mohamed  1 , Ahmed Daoud  2 , Syed Quadri  3 , Michael J Casey  3 , Mariah Aurora Posadas Salas  3 , Vinaya Rao  3 , Tibor Fülöp  3 , Karim M Soliman  4
Affiliations
Review

Hypertension and obesity in living kidney donors

Mahmoud M Mohamed et al. World J Transplant. .

Abstract

Over the past few decades, the shortage in the kidney donor pool as compared to the increasing number of candidates on the kidney transplant waitlist led to loosening of kidney donors' acceptance criteria. Hypertension and obesity represent risk factors for chronic kidney disease, both in native kidneys and those in kidney transplant recipients. While great progress has been made in kidney transplantation from living donors to benefit the recipient survival and quality of life, progress has been slow to fully risk-characterize the donors. This review critically reassesses the current state of understanding regarding the risk of end-stage kidney disease in those donors with obesity, hypertension or both. Accurate risk assessment tools need to be developed urgently to fully understand the risk glomerular filtration rate compensation failure in the remaining kidney of the donors.

Keywords: Hypertension; Kidney; Living donor; Living kidney donors; Obesity.

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Conflict of interest statement

Conflict-of-interest statement: The authors declare no conflicts of interest.

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