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Case Reports
. 2021 Jun 10:25:e01182.
doi: 10.1016/j.idcr.2021.e01182. eCollection 2021.

A fatal case of disseminated mucormycosis in an immunocompetent patient post traumatic injury

Lama Arfaj  1 , Fatinah Aloqpi  1 , Waleed Elsayad  1 , Sarah Tayeb  1 , Nada Rabie  1 , Mohammed Samannodi  1   2
Affiliations
Case Reports

A fatal case of disseminated mucormycosis in an immunocompetent patient post traumatic injury

Lama Arfaj et al. IDCases. .

Abstract

Mucormycosis, is an invasive infection caused by fungi. Mainly it affects patients with immunosuppressive conditions but can occur in immuncompetent host in specific situation such us direct skin inoculation by traumatic injury. We present a 56-year-old patient who hospitalized due to left orbital cellulitis and necrotizing fasciitis post traumatic injury. A diagnosis of invasive mucormycosis was established by tissue histopathology and culture. Despite daily surgical debridement and amphotericin B, the infection disseminated to central nervous system led to fatal outcome. We conclude that mucormycosis can disseminate in immunocompetent population and leads to death.

Keywords: Immunocompetent; Invasive; Mucormycosis; Trauma.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Left eye ecchymosis and swelling on first day of hospitalization.
Fig. 2
Fig. 2
(A) CT of head showed opacification of left frontal, sphenoid, ethmoid and maxillary sinuses suggestive for sinusitis. (B) MRI of head showed inflammatory changes of left infra-temporal fossa and left masticator along with signs left sinusitis.
Fig. 3
Fig. 3
Histopathology of multiple fungal hyphae with angioinvasion.
Fig. 4
Fig. 4
Left facial necrotic tissues with blackish discoloration.
Fig. 5
Fig. 5
Mucor spp. grew from orbital tissue culture.
See this image and copyright information in PMC

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