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. 2021 Jun 25;14(1):240.
doi: 10.1186/s13104-021-05569-w.

First insights into molecular basis identification of 16 s ribosomal RNA gene of Staphylococcus aureus isolated from Sudan

Manal A Gumaa  1 , Abeer Babiker Idris  2 , N E Bilal  3 , Mohamed A Hassan  4
Affiliations

First insights into molecular basis identification of 16 s ribosomal RNA gene of Staphylococcus aureus isolated from Sudan

Manal A Gumaa et al. BMC Res Notes. .

Abstract

Objective: In this study, we analyzed the molecular evolution of Staphylococcus aureus isolates using 16S rRNA gene and phylogenetic analysis to detect the prevalence of S. aureus infections in Sudan.

Results: Molecular detection of S. aureus has shown that 20 (43.47%) of patients were positive for S. aureus. The phylogenetic tree of 16S rRNA sequences was divided into three lineages of S. aureus isolates detected from wound infections in Sudan. Nucleotides base-pair substitution was appeared at position 249. This mutation do not linked with Macrolides, Lincosamides and Streptogramines b resistant phenotype. Further studies should investigate the effect of that mutation on resistance to other antibiotics.

Keywords: 16S rRNA gene; Phylogenetic tree; Staphylococcus aureus.

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Conflict of interest statement

The authors declare that there are no conflicts of interest.

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