Effect of high-dose baclofen on agitation-related events among patients with unhealthy alcohol use receiving mechanical ventilation: Plea for a pharmacodynamic monitoring, the EEG

Affiliations

¹ Neuro-Intensive Care Unit, Rothschild Foundation Hospital, 29, Rue Manin, 75940 Paris Cedex 19, France. Electronic address: nengrand@for.paris.
² Neuro-Intensive Care Unit, Rothschild Foundation Hospital, 29, Rue Manin, 75940 Paris Cedex 19, France.
³ Neurology Department, University of Strasbourg, Hautepierre Hospital, 5, Avenue Molière, 67200 Strasbourg, France.

Comment

Nicolas Engrand et al. Anaesth Crit Care Pain Med. 2021 Aug.

. 2021 Aug;40(4):100910.

doi: 10.1016/j.accpm.2021.100910. Epub 2021 Jun 24.

¹ Neuro-Intensive Care Unit, Rothschild Foundation Hospital, 29, Rue Manin, 75940 Paris Cedex 19, France. Electronic address: nengrand@for.paris.
² Neuro-Intensive Care Unit, Rothschild Foundation Hospital, 29, Rue Manin, 75940 Paris Cedex 19, France.
³ Neurology Department, University of Strasbourg, Hautepierre Hospital, 5, Avenue Molière, 67200 Strasbourg, France.

No abstract available

Keywords: Alcohol abuse; Alcohol withdrawal; Baclofen ICU; EEG.

Comment on

Effect of High-Dose Baclofen on Agitation-Related Events Among Patients With Unhealthy Alcohol Use Receiving Mechanical Ventilation: A Randomized Clinical Trial.
Vourc'h M, Garret C, Gacouin A, Lacherade JC, Jonas M, Klouche K, Ferrandiere M, Jaber S, Flet L, Dailly E, Pouplet C, Maamar A, Reignier J, Roquilly A, Feuillet F, Mahe PJ, Asehnoune K; BACLOREA study group. Vourc'h M, et al. JAMA. 2021 Feb 23;325(8):732-741. doi: 10.1001/jama.2021.0658. JAMA. 2021. PMID: 33620407 Free PMC article. Clinical Trial.