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Case Reports
. 2021 May 24;13(5):e15210.
doi: 10.7759/cureus.15210.

Giant Congenital Melanocytic Nevi in a Pakistani Newborn

Affiliations
Case Reports

Giant Congenital Melanocytic Nevi in a Pakistani Newborn

Hina Mumtaz Hashmi et al. Cureus. .

Abstract

Congenital melanocytic nevi arise from overgrowth or disrupted migration of melanocyte precursor in the neural crest. They are also known as coat-sleeve, stocking, bathing trunk or garment nevi. The colour ranges from brown to black, with the lesions presenting as flat to raised nevi. Lesions presenting at birth with a diameter greater than 20cm are labelled giant congenital melanocytic nevi. Risk increases with an increase in the number of satellite lesions near the giant nevus. Management includes regular clinical follow-up monitoring of changes in the lesion and surgical procedures in cases with risk of melanoma and psychological support. The purpose of this case presentation is to describe a rare issue of giant congenital melanocytic nevi in a newborn, along with a literature review and discussion on possible management options.

Keywords: giant congenital melanocytic nevi; melanoma; neurocutaneous melanosis; nevomelanocytes; satellite lesions.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Giant congenital melanocytic nevus over back with nodules and pigmentation
Figure 2
Figure 2. Multiple satellite lesions and small lesions over nape of neck and upper back

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References

    1. New recommendations for the categorization of cutaneous features of congenital melanocytic nevi. Krengel S, Scope A, Dusza SW, Vonthein R, Marghoob AA. https://pubmed.ncbi.nlm.nih.gov/22982004/ J Am Acad Dermatol. 2013;68:441–451. - PubMed
    1. Giant congenital melanocytic nevi: a case report. Das SK, Amarendra M, Subudhi M. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576774/#. J Clin Diagn Res. 2012;7:154–155. - PMC - PubMed
    1. Giant congenital melanocytic nevus . Viana ACL, Gontijo B, Bittencourt FV. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900335/ An Bras Dermatol. 2013;88:863–878. - PMC - PubMed
    1. Congenital melanocytic nevi: where are we now? Part II. treatment options and approach to treatment. Ibrahimi OA, Alikhan A, Eisen DB. https://pubmed.ncbi.nlm.nih.gov/22980259/ J Am Acad Dermatol. 2012;67:0–13. - PubMed
    1. Giant congenital melanocytic nevus treated with trametinib. Mir A, Agim NG, Kane AA, Josephs SC, Park JY, Ludwig K. https://doi.org/10.1542/peds.2018-2469 Pediatrics. 2019;143:0. - PubMed

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