Giant Congenital Melanocytic Nevi in a Pakistani Newborn
- PMID: 34178529
- PMCID: PMC8221640
- DOI: 10.7759/cureus.15210
Giant Congenital Melanocytic Nevi in a Pakistani Newborn
Abstract
Congenital melanocytic nevi arise from overgrowth or disrupted migration of melanocyte precursor in the neural crest. They are also known as coat-sleeve, stocking, bathing trunk or garment nevi. The colour ranges from brown to black, with the lesions presenting as flat to raised nevi. Lesions presenting at birth with a diameter greater than 20cm are labelled giant congenital melanocytic nevi. Risk increases with an increase in the number of satellite lesions near the giant nevus. Management includes regular clinical follow-up monitoring of changes in the lesion and surgical procedures in cases with risk of melanoma and psychological support. The purpose of this case presentation is to describe a rare issue of giant congenital melanocytic nevi in a newborn, along with a literature review and discussion on possible management options.
Keywords: giant congenital melanocytic nevi; melanoma; neurocutaneous melanosis; nevomelanocytes; satellite lesions.
Copyright © 2021, Mumtaz Hashmi et al.
Conflict of interest statement
The authors have declared that no competing interests exist.
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References
-
- New recommendations for the categorization of cutaneous features of congenital melanocytic nevi. Krengel S, Scope A, Dusza SW, Vonthein R, Marghoob AA. https://pubmed.ncbi.nlm.nih.gov/22982004/ J Am Acad Dermatol. 2013;68:441–451. - PubMed
-
- Giant congenital melanocytic nevi: a case report. Das SK, Amarendra M, Subudhi M. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576774/#. J Clin Diagn Res. 2012;7:154–155. - PMC - PubMed
-
- Giant congenital melanocytic nevus . Viana ACL, Gontijo B, Bittencourt FV. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900335/ An Bras Dermatol. 2013;88:863–878. - PMC - PubMed
-
- Congenital melanocytic nevi: where are we now? Part II. treatment options and approach to treatment. Ibrahimi OA, Alikhan A, Eisen DB. https://pubmed.ncbi.nlm.nih.gov/22980259/ J Am Acad Dermatol. 2012;67:0–13. - PubMed
-
- Giant congenital melanocytic nevus treated with trametinib. Mir A, Agim NG, Kane AA, Josephs SC, Park JY, Ludwig K. https://doi.org/10.1542/peds.2018-2469 Pediatrics. 2019;143:0. - PubMed
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