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Meta-Analysis
. 2021 Dec 17;109(1):12-14.
doi: 10.1093/bjs/znab221.

Acute pancreatitis in pregnancy: meta-analysis of maternal and fetal outcomes

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Meta-Analysis

Acute pancreatitis in pregnancy: meta-analysis of maternal and fetal outcomes

D Ll Hughes et al. Br J Surg. .

Abstract

The impact of acute pancreatitis in pregnancy on maternal and fetal outcomes is unclear. Historical case series document very poor outcomes, with maternal mortality rates of 20 per cent and fetal loss of 50 per cent. However, this is based on outdated clinical practice. This meta-analysis quantified both maternal and fetal outcomes following acute pancreatitis in pregnancy based on the concurrent literature. Maternal and fetal outcomes after acute pancreatitis in pregnancy have improved with advances in the management of pancreatitis.

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Fig. 1
Fig. 1
Meta-analysis of pooled maternal and fetal mortality rates a Maternal and b fetal mortality. A random-effects model was used for meta-analysis. Proportions are shown with 95 per cent confidence intervals.

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