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Editorial
. 2021 Sep 10;39(26):2851-2854.
doi: 10.1200/JCO.21.01296. Epub 2021 Jun 28.

A Step Forward in Realizing the Promise of Genomic Medicine for Childhood Rhabdomyosarcoma

Affiliations
Editorial

A Step Forward in Realizing the Promise of Genomic Medicine for Childhood Rhabdomyosarcoma

Leo Mascarenhas. J Clin Oncol. .
No abstract available

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Conflict of interest statement

Leo MascarenhasConsulting or Advisory Role: BayerSpeakers' Bureau: BayerResearch Funding: AstraZeneca/MedImmune, Lilly, Bayer, Loxo, Salarius Pharmaceuticals, Turning Point Therapeutics, Pfizer, Incyte, AmgenTravel, Accommodations, Expenses: Bayer, Lilly, Thermo Fisher Scientific, Salarius PharmaceuticalsUncompensated Relationships: Children's Oncology Group Foundation, The Pablove Foundation, American Society of Pediatric Hematology/OncologyNo other potential conflicts of interest were reported.

Comment on

  • Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium.
    Shern JF, Selfe J, Izquierdo E, Patidar R, Chou HC, Song YK, Yohe ME, Sindiri S, Wei J, Wen X, Rudzinski ER, Barkauskas DA, Lo T, Hall D, Linardic CM, Hughes D, Jamal S, Jenney M, Chisholm J, Brown R, Jones K, Hicks B, Angelini P, George S, Chesler L, Hubank M, Kelsey A, Gatz SA, Skapek SX, Hawkins DS, Shipley JM, Khan J. Shern JF, et al. J Clin Oncol. 2021 Sep 10;39(26):2859-2871. doi: 10.1200/JCO.20.03060. Epub 2021 Jun 24. J Clin Oncol. 2021. PMID: 34166060 Free PMC article.

References

    1. Gurney JG, Young JL, Roffers SD, et al. : Soft Tissue Sarcomas. Bethesda, MD, NIH, 1999
    1. Newton WA Jr, Gehan EA, Webber BL, et al. :Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification—An Intergroup Rhabdomyosarcoma Study. Cancer 76:1073-1085, 1995 - PubMed
    1. Loh WE Jr, Scrable HJ, Livanos E, et al. :Human chromosome 11 contains two different growth suppressor genes for embryonal rhabdomyosarcoma. Proc Natl Acad Sci USA 89:1755-1759, 1992 - PMC - PubMed
    1. Barr FG, Galili N, Holick J, et al. :Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma. Nat Genet 3:113-117, 1993 - PubMed
    1. Davis RJ, D'Cruz CM, Lovell MA, et al. :Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res 54:2869-2872, 1994 - PubMed