A Novel atTAK Against Hepatocellular Carcinoma: Overcoming Resistance to Sorafenib
- PMID: 34181901
- PMCID: PMC8413139
- DOI: 10.1016/j.jcmgh.2021.06.005
A Novel atTAK Against Hepatocellular Carcinoma: Overcoming Resistance to Sorafenib
Comment on
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TAK1 Is a Novel Target in Hepatocellular Carcinoma and Contributes to Sorafenib Resistance.Cell Mol Gastroenterol Hepatol. 2021;12(3):1121-1143. doi: 10.1016/j.jcmgh.2021.04.016. Epub 2021 May 5. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33962073 Free PMC article.
References
-
- Siegel R.L., Miller K.D., Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020;70:7–30. - PubMed
-
- Llovet J.M., Ricci S., Mazzaferro V., Hilgard P., Gane E., Blanc J.F., de Oliveira A.C., Santoro A., Raoul J.L., Forner A., Schwartz M., Porta C., Zeuzem S., Bolondi L., Greten T.F., Galle P.R., Seitz J.F., Borbath I., Haussinger D., Giannaris T., Shan M., Moscovici M., Voliotis D., Bruix J., SHARP Investigators Study Group Sorafenib in advanced hepatocellular carcinoma. N Engl J Med. 2008;359:378–390. - PubMed
-
- Finn R.S., Qin S., Ikeda M., Galle P.R., Ducreux M., Kim T.Y., Kudo M., Breder V., Merle P., Kaseb A.O., Li D., Verret W., Xu D.Z., Hernandez S., Liu J., Huang C., Mulla S., Wang Y., Lim H.Y., Zhu A.X., Cheng A.L. IMbrave 150 Investigators. Atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma. N Engl J Med. 2020;382:1894–1905. - PubMed
-
- Santoro R., Carbone C., Piro G., Chiao P.J., Melisi D. TAK-ing aim at chemoresistance: the emerging role of MAP3K7 as a target for cancer therapy. Drug Resist Updat. 2017;33-35:36–42. - PubMed
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