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Review
. 2021 Sep:98:107909.
doi: 10.1016/j.intimp.2021.107909. Epub 2021 Jun 25.

Pattern recognition receptors as therapeutic targets for bacterial, viral and fungal sepsis

Koichi Yuki  1 , Sophia Koutsogiannaki  2
Affiliations
Review

Pattern recognition receptors as therapeutic targets for bacterial, viral and fungal sepsis

Koichi Yuki et al. Int Immunopharmacol. 2021 Sep.

Abstract

Sepsis remains to be a significant health care problem associated with high morbidities and mortalities. Recognizing its heterogeneity, it is critical to understand our host immunological responses to develop appropriate therapeutic approaches according to the type of sepsis. Because pattern recognition receptors are largely responsible for the recognition of microbes, we reviewed their role in immunological responses in the setting of bacterial, fungal and viral sepsis. We also considered their therapeutic potentials in sepsis.

Keywords: Bacteria; Fungus; Pattern recognition receptors; Sepsis; Virus.

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Conflict of interest statement

Conflict of Interest:

None

Figures

Figure 1.
Figure 1.
Pattern recognition receptors involved in bacterial, viral and fungal sepsis
See this image and copyright information in PMC

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