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Comment
. 2021 Jul 1;116(7):1556.
doi: 10.14309/ajg.0000000000001174.

Irritable Bowel Syndrome and Functional Dyspepsia: Different Ends of the Same Spectrum of Intestinal Barrier Dysfunction?

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Comment

Irritable Bowel Syndrome and Functional Dyspepsia: Different Ends of the Same Spectrum of Intestinal Barrier Dysfunction?

Daniel Keszthelyi. Am J Gastroenterol. .
No abstract available

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Comment in

  • Response to Keszthelyi.
    Nojkov B, Chey WD. Nojkov B, et al. Am J Gastroenterol. 2021 Jul 1;116(7):1557. doi: 10.14309/ajg.0000000000001251. Am J Gastroenterol. 2021. PMID: 33767099 No abstract available.

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References

    1. Nojkov B, Zhou SY, Dolan RD, et al. Evidence of duodenal epithelial barrier impairment and increased pyroptosis in patients with functional dyspepsia on confocal laser endomicroscopy and ex vivo mucosa analysis. Am J Gastroenterol 2020;115(11):1891–901.
    1. Mujagic Z, Jonkers D, Masclee AAM, et al. A key role for the small bowel in irritable bowel syndrome pathophysiology: Time to refocus? Clin Gastroenterol Hepatol 2021;19(2):409–10.
    1. Fritscher-Ravens A, Schuppan D, Ellrichmann M, et al. Confocal endomicroscopy shows food-associated changes in the intestinal mucosa of patients with irritable bowel syndrome. Gastroenterology 2014;147:1012–20.e4.
    1. Turcotte JF, Kao D, Mah SJ, et al. Breaks in the wall: Increased gaps in the intestinal epithelium of irritable bowel syndrome patients identified by confocal laser endomicroscopy (with videos). Gastrointest Endosc 2013;77:624–30.
    1. Robles-Medranda C, Oleas R, Valero M, et al. Confocal laser endomicroscopy detects colonic inflammation in patients with irritable bowel syndrome: A prospective study. Endosc Int Open 2020;8:E550–7.

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