Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jul;17(3):499-500.
doi: 10.3988/jcn.2021.17.3.499.

A Case of Cortical Involvement in Marchiafava-Bignami Disease Accompanying Wernicke's Encephalopathy

Michelle Youn  1 , Jung Ju Lee  2 , Jong Moo Park  3 , Kyusik Kang  1 , Ohyun Kwon  3 , Woong Woo Lee  1 , Byung Kun Kim  1
Affiliations

A Case of Cortical Involvement in Marchiafava-Bignami Disease Accompanying Wernicke's Encephalopathy

Michelle Youn et al. J Clin Neurol. 2021 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have no potential conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1. Brain magnetic resonance imaging (MRI) images with fluid-attenuated inversion recovery (A–D) and diffusion-weighted MRI images (E–H) of our patient. High signal intensities in the periaqueductal gray and bilateral medial thalami are evident in panels A and B (long arrows). Widespread high signal intensities involving the corpus callosum are evident in panels B, C, F, and G (short arrows). Linear high signal intensities are evident in the bilateral frontal cortices in panels D and H (double head arrows).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Tsui EYK, Man BL, Fu M, Chan JHM, Yuen MK, Ng SH. Coexistence of Marchiafava-Bignami disease, Wernicke encephalopathy and central pontine myelinolysis in a patient with chronic alcoholism. Eur J Radiol Extra. 2003;48:74–77.
    1. Gerlach A, Oehm E, Wattchow J, Ziyeh S, Glocker FX, Els T. Use of high-dose cortisone in a patient with Marchiafava-Bignami disease. J Neurol. 2003;250:758–760. - PubMed
    1. Kim MJ, Kim JK, Yoo BG, Kim KS, Jo YD. Acute Marchiafava-Bignami disease with widespread callosal and cortical lesions. J Korean Med Sci. 2007;22:908–911. - PMC - PubMed
    1. White ML, Zhang Y, Andrew LG, Hadley WL. MR imaging with diffusion-weighted imaging in acute and chronic Wernicke encephalopathy. AJNR Am J Neuroradiol. 2005;26:2306–2310. - PMC - PubMed
    1. Jung JW, Hwang IG, Park HS, Koh IS, Kim HK. Rapid recovery from Marchiafava-Bignami disease after intravenous corticosteroid administration. J Neurocrit Care. 2015;8:25–29.