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. 2021 Jul;17(3):499-500.
doi: 10.3988/jcn.2021.17.3.499.

A Case of Cortical Involvement in Marchiafava-Bignami Disease Accompanying Wernicke's Encephalopathy

Michelle Youn  1 , Jung Ju Lee  2 , Jong Moo Park  3 , Kyusik Kang  1 , Ohyun Kwon  3 , Woong Woo Lee  1 , Byung Kun Kim  1
Affiliations

A Case of Cortical Involvement in Marchiafava-Bignami Disease Accompanying Wernicke's Encephalopathy

Michelle Youn et al. J Clin Neurol. 2021 Jul.
No abstract available

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Conflict of interest statement

The authors have no potential conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1. Brain magnetic resonance imaging (MRI) images with fluid-attenuated inversion recovery (A–D) and diffusion-weighted MRI images (E–H) of our patient. High signal intensities in the periaqueductal gray and bilateral medial thalami are evident in panels A and B (long arrows). Widespread high signal intensities involving the corpus callosum are evident in panels B, C, F, and G (short arrows). Linear high signal intensities are evident in the bilateral frontal cortices in panels D and H (double head arrows).
See this image and copyright information in PMC

References

    1. Tsui EYK, Man BL, Fu M, Chan JHM, Yuen MK, Ng SH. Coexistence of Marchiafava-Bignami disease, Wernicke encephalopathy and central pontine myelinolysis in a patient with chronic alcoholism. Eur J Radiol Extra. 2003;48:74–77.
    1. Gerlach A, Oehm E, Wattchow J, Ziyeh S, Glocker FX, Els T. Use of high-dose cortisone in a patient with Marchiafava-Bignami disease. J Neurol. 2003;250:758–760. - PubMed
    1. Kim MJ, Kim JK, Yoo BG, Kim KS, Jo YD. Acute Marchiafava-Bignami disease with widespread callosal and cortical lesions. J Korean Med Sci. 2007;22:908–911. - PMC - PubMed
    1. White ML, Zhang Y, Andrew LG, Hadley WL. MR imaging with diffusion-weighted imaging in acute and chronic Wernicke encephalopathy. AJNR Am J Neuroradiol. 2005;26:2306–2310. - PMC - PubMed
    1. Jung JW, Hwang IG, Park HS, Koh IS, Kim HK. Rapid recovery from Marchiafava-Bignami disease after intravenous corticosteroid administration. J Neurocrit Care. 2015;8:25–29.