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Review
. 2021;121(5):138-143.
doi: 10.17116/jnevro2021121051138.

[Polyneuropathies during COVID-19 epidemics]

[Article in Russian]
M L Chukhlovina  1
Affiliations
Review

[Polyneuropathies during COVID-19 epidemics]

[Article in Russian]
M L Chukhlovina. Zh Nevrol Psikhiatr Im S S Korsakova. 2021.

Abstract
in English, Russian

Our review article aimed for analysis of pathogenesis, diagnostyics and treatment of polyneuropathies manifesting in the course of COVID-19. The reasons for hyposmia and taste disturbances are considered in the subjects with this coronavirus infection as well as relationship between these clinical manifestations and severity of the viral infection. Special attention is given to description of autoimmune mechanisms of Guillain-Barré syndrome and polyneuropathies of critical conditions associated with COVID-19. Some data report about clinical deterioration of diabetic and alcoholic neuropathy during the SARS-CoV-2 infection. Inclusion of group B vitamins, together with C and D vitamins, is recommended to the schedules of combined treatment for polyneuropathies in these patients. Early diagnostics of polyneuropathies, especially, Guillain-Barré syndrome, is required during COVID-19 pandemics, thus helping to administer rational therapy and promoting better quality of life in the patients.

Проведен анализ особенностей патогенеза, диагностики и терапии полинейропатий в условиях COVID-19. Рассмотрены причины развития гипосмии и гипогевзии у лиц, переносящих коронавирусную инфекцию, взаимосвязь клинических проявлений с тяжестью вирусного заболевания. Особое внимание уделено описанию аутоиммунных механизмов синдрома Гийена—Барре и полинейропатии критических состояний, ассоциированных с COVID-19. Приведены данные о том, что течение диабетической и алкогольной полинейропатии ухудшается на фоне коронавирусной инфекции. Отмечена необходимость включения витаминов группы В в сочетании с витаминами D и С в комплексную терапию полинейропатии у таких пациентов. В условиях пандемии COVID-19 необходима ранняя диагностика полинейропатий, особенно синдрома Гийена—Барре, что будет способствовать проведению рациональной терапии, улучшению прогноза, качества жизни пациентов.

Keywords: Guillain-Barré syndrome; Neuromultivit; SARS-CoV-2; alcoholic neuropathy; diabetic neuropathy.

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