Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Aug;23(5-6):476-479.
doi: 10.1080/21678421.2021.1946088. Epub 2021 Jun 30.

ALSUntangled #62: vitamin C

Richard Bedlack  1 , Paul Barkhaus  2 , Greg Carter  3 , Jesse Crayle  4 , Christopher Mcdermott  5 , Gary Pattee  6 , Meraida Polak  7 , Kristiana Salmon  8 , Paul Wicks  9
Affiliations

ALSUntangled #62: vitamin C

Richard Bedlack et al. Amyotroph Lateral Scler Frontotemporal Degener. 2022 Aug.

Abstract

Vitamin C is one of the most common supplements taken by people with ALS. As an antioxidant, it has a plausible mechanism for slowing disease progression and there are some flawed pre-clinical studies and case reports suggesting benefit. However, a small human trial showed no benefit. Given this negative trial, we do not currently advise vitamin C as an ALS treatment.

Keywords: Vitamin C; acorbic acid; ascorbate; clinical trials; models; therapy.

PubMed Disclaimer

LinkOut - more resources