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Case Reports
. 2021 Mar-Apr;66(2):191-194.
doi: 10.4103/ijd.IJD_218_20.

Neutrophilic Dermatosis of the Hands with Palmar Involvement and Predominant Lymphomononuclear Cell Infiltration

Avik Panigrahi  1 , Surajit K Biswas  1 , Abheek Sil  1 , Dibyendu B Bhanja  1
Affiliations
Case Reports

Neutrophilic Dermatosis of the Hands with Palmar Involvement and Predominant Lymphomononuclear Cell Infiltration

Avik Panigrahi et al. Indian J Dermatol. 2021 Mar-Apr.

Abstract

Neutrophilic dermatosis of the hands (NDH) is a rare localized acral variant of Sweet syndrome. NDH predominantly involves the dorsal hands with characteristic dense dermal neutrophilic infiltrate with an upper dermal edema observed on histopathology. Unusual findings like palmar involvement and predominant lymphomononuclear dermal infiltration in our case with NDH, makes it an interesting read.

Keywords: Acral Sweet sysndrome; lymphocytic infiltration; neutrophilic dermatosis of the hands; palmar involvement.

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Conflict of interest statement

The authors of this article have no conflict of interest.

Figures

Figure 1
Figure 1
Multiple erythematous to violaceous plaques symmetrically distributed over both palms and the dorsa of feet. Larger lesions showing pseudo-vesicular appearance
Figure 2
Figure 2
(a): Histopathological examination showing marked papillary dermal edema with upper and mid-dermal lymphomononuclear cell infiltrate (H&E, 40×). (b): Higher magnification showing papillary dermal and perivascular infiltrate, consisting of predominantly lymphocytes, very few neutrophils with few extravasated erythrocytes. No features of vasculitis seen (H&E, 400×)
Figure 3
Figure 3
Significant improvement of the lesions following treatment with systemic corticosteroid
See this image and copyright information in PMC

References

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