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. 1990 Jan;32(3):13-15.
doi: 10.1093/ilar.32.3.13.

WKY Fatty Rat as a Model of Obesity and Non-insulin-dependent Diabetes Mellitus

Richard G Peterson, Leah A Little, Mary-Ann Neel

WKY Fatty Rat as a Model of Obesity and Non-insulin-dependent Diabetes Mellitus

Richard G Peterson et al. Ilar News. 1990 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Comparative weight gains between pre-cesareanderived and post-cesarean-derived WKY/NDrt-fa/fa rats. The precesarean derivation data are from a combined group of N8 and N10 backcrossed rats, and the post-cesarean derivation data are from N10 rats. There are from 12 to 16 rats represented at each data point in the pre-cesarean derivation data and 5 to 12 in the post-cesarean derivation curve. There is an obvious delay in weight gain for the pre-cesarean-derived group of rats, with a significant difference between the two groups of rats at each time point. Data are presented as mean ± SD.
Figure 2
Figure 2
Blood glucose levels over time for pre- and postcesarean-derived WKY/NDrt-fa/fa rats fed ad libitum. These data are from the same groups of rats represented in Figure 1. The precesarean-derived rats do not show any rise in blood glucose, whereas the post-cesarean-derived rats show a very significant rise in blood glucose level over time. Data are presented as mean ± SD.
See this image and copyright information in PMC

References

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    1. Clark J. B., Palmer C. J., Shaw W. N. 1983. The diabetic Zucker fatty rat. Proc. Soc. Exp. Biol. Med. 173:68–75. - PubMed
    1. Ikeda H., Shino A., Matsuo T. 1981. A new genetically obesehyperglycemic rat (Wistar fatty). Diabetes 30:1045–1050. - PubMed

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