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Review
. 2021 Jun 14:15:680938.
doi: 10.3389/fnins.2021.680938. eCollection 2021.

Directions of Deep Brain Stimulation for Epilepsy and Parkinson's Disease

Ying-Chang Wu  1 , Ying-Siou Liao  1 , Wen-Hsiu Yeh  2 , Sheng-Fu Liang  1   3 , Fu-Zen Shaw  2   4
Affiliations
Review

Directions of Deep Brain Stimulation for Epilepsy and Parkinson's Disease

Ying-Chang Wu et al. Front Neurosci. .

Abstract

Background: Deep brain stimulation (DBS) is an effective treatment for movement disorders and neurological/psychiatric disorders. DBS has been approved for the control of Parkinson disease (PD) and epilepsy.

Objectives: A systematic review and possible future direction of DBS system studies is performed in the open loop and closed-loop configuration on PD and epilepsy.

Methods: We searched Google Scholar database for DBS system and development. DBS search results were categorized into clinical device and research system from the open-loop and closed-loop perspectives.

Results: We performed literature review for DBS on PD and epilepsy in terms of system development by the open loop and closed-loop configuration. This study described development and trends for DBS in terms of electrode, recording, stimulation, and signal processing. The closed-loop DBS system raised a more attention in recent researches.

Conclusion: We overviewed development and progress of DBS. Our results suggest that the closed-loop DBS is important for PD and epilepsy.

Keywords: PD; closed-loop; deep brain stimulation; epilepsy; open loop.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Schematic plot of a technical system for deep brain stimulation (top) and its flowchart of signal processing (bottom).
FIGURE 2
FIGURE 2
Publications utilizes the open loop and closed-loop architecture in the control of PD (A) and epilepsy (B).
See this image and copyright information in PMC

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