Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2021 Jun 22;12(13):1318-1320.
doi: 10.18632/oncotarget.27967.

The formation of pre-effectors in the steady state opens a new perspective for cancer immunosurveillance

Alexey Surnov, Daniel Hawiger
Editorial

The formation of pre-effectors in the steady state opens a new perspective for cancer immunosurveillance

Alexey Surnov et al. Oncotarget. .
No abstract available

Keywords: Hopx; cancer immunosurveillance; dendritic cells; pre-effectors; steady state.

PubMed Disclaimer

Conflict of interest statement

CONFLICTS OF INTEREST Authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1. Hopx-expressing (Hopxhi) CD4+ pre-effectors are epigenetically and transcriptionally programmed in the steady state by dendritic cells in response to various antigens.
These Hopxhi pre-effectors can readily terminally differentiate into effectors. The mechanisms of differentiation of such effectors that could contribute to anti-tumor responses remain to be investigated.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Cancel JC, et al.. Front Immunol. 2019; 10:9. 10.3389/fimmu.2019.00009. - DOI - PMC - PubMed
    1. Theisen DJ, et al.. Science. 2018; 362:694–99. 10.1126/science.aat5030. - DOI - PMC - PubMed
    1. Corthay A, et al.. Immunity. 2005; 22:371–83. 10.1016/j.immuni.2005.02.003. - DOI - PubMed
    1. Alspach E, et al.. Nature. 2019; 574:696–701. 10.1038/s41586-019-1671-8. - DOI - PMC - PubMed
    1. Jhunjhunwala SC, et al.. Nat Rev Cancer. 2021; 21:298–312. 10.1038/s41568-021-00339-z. - DOI - PubMed

Publication types

LinkOut - more resources