Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 May;10(5):1814-1817.
doi: 10.4103/jfmpc.jfmpc_2108_20. Epub 2021 May 31.

Role of radiology in RT-PCR negative COVID-19 pneumonia: Review and recommendations

Affiliations
Review

Role of radiology in RT-PCR negative COVID-19 pneumonia: Review and recommendations

Binit Sureka et al. J Family Med Prim Care. 2021 May.

Abstract

Currently, RT-PCR is the gold standard for diagnosing SARS-CoV-2 infection. However, due to the time-consuming laboratory tests and the low positivity rate of RT-PCR, it cannot be an ideal screening tool for infected population. In this review article, we have reviewed studies related to RT-PCR and CT chest and we would like to give our recommendations. Depending upon the patient's clinical symptoms and radiology imaging typical of viral pneumonia compatible with COVID-19 infection, clinicians need to consider isolation of these patients early even if the RT-PCR test is negative.

Keywords: COVID-19; CT; RT-PCR; negative.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

References

    1. Kim HW, Capaccione KM, Li G, Luk L, Widemon RS, Rahman O, et al. The role of initial chest X-ray in triaging patients with suspected COVID-19 during the pandemic. Emerg Radiol. 2020;27:610–21. - PMC - PubMed
    1. Ministry of Health and Family Welfare [Internet] cited 2020 April 04. Available from: https://www.mohfw.gov.in/
    1. Zu ZY, Jiang MD, Xu PP, Chen W, Ni QQ, Lu GM, et al. Coronavirus disease 2019 (COVID-19): A perspective from China. Radiology. 2020;296:E15–25. - PMC - PubMed
    1. Long C, Xu H, Shen Q, Zhang X, Fan B, Wang C, et al. Diagnosis of the Coronavirus disease (COVID-19): rRT-PCR or CT? Eur J Radiol. 2020;126:108961. - PMC - PubMed
    1. Kucirka LM, Lauer SA, Laeyendecker O, Boon D, Lessler J. Variation in false-negative rate of reverse transcriptase polymerase chain reaction–based SARS-CoV-2 tests by time since exposure. Ann Intern Med. 2020;173:262–7. - PMC - PubMed