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Observational Study
. 2022 Apr;157(1):76-84.
doi: 10.1002/ijgo.13810. Epub 2021 Jul 27.

Uterine rupture during pregnancy: The URIDA (uterine rupture international data acquisition) study

Andrea Tinelli  1   2   3   4 , Ioannis P Kosmas  3   5 , Jose Tony Carugno  6 , Howard Carp  7 , Antonio Malvasi  3   8 , Shlomo B Cohen  7 , Antonio Simone Laganà  9 , Marta Angelini  10 , Paolo Casadio  11 , Jenifer Chayo  7 , Ettore Cicinelli  12 , Sandro Gerli  13 , Josè Palacios Jaraquemada  14 , Giulia Magnarelli  11 , Mykhailo V Medvediev  15 , Josè Metello  16 , Luigi Nappi  17 , Jude Okohue  18 , Radmila Sparic  19 , Radomir Stefanović  19 , Avinoam Tzabari  20 , Antonella Vimercati  12
Affiliations
Observational Study

Uterine rupture during pregnancy: The URIDA (uterine rupture international data acquisition) study

Andrea Tinelli et al. Int J Gynaecol Obstet. 2022 Apr.

Abstract

Objective: To describe the characteristics and peripartum outcomes of patients diagnosed with uterine rupture (UR) by an observational cohort retrospective study on 270 patients.

Methods: Demographic information, surgical history, symptoms, and postoperative outcome of women and neonates after UR were collected in a large database. The statistical analysis searched for correlation between UR, previous uterine interventions, fibroids, and the successive perinatal outcomes in women with previous UR.

Results: Uterine rupture was significantly associated with previous uterine surgery, occurring, on average, at 36 weeks of pregnancy in women also without previous uterine surgery. UR did not rise exponentially with an increasing number of uterine operations. Fibroids were related to UR. The earliest UR occurred at 159 days after hysteroscopic myomectomy, followed by laparoscopic myomectomy (251 days) and laparotomic myomectomy (253 days). Fertility preservation was feasible in several women. Gestational age and birth weight seemed not to be affected in the subsequent pregnancy.

Conclusion: Data analysis showed that previous laparoscopic and abdominal myomectomies were associated with UR in pregnancy, and hysteroscopic myomectomy was associated at earlier gestational ages. UR did not increase exponentially with an increasing number of previous scars. UR should not be considered a contraindication to future pregnancies.

Keywords: cesarean sections; labor management; myomectomy; pregnancy; related complications; uterine rupture.

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References

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