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Review
. 2021 Jun 2;26(11):3362.
doi: 10.3390/molecules26113362.

The Use of Megamolecular Polysaccharide Sacran in Food and Biomedical Applications

Lisa Efriani Puluhulawa  1 , I Made Joni  2   3 , Ahmed Fouad Abdelwahab Mohammed  4 , Hidetoshi Arima  5 , Nasrul Wathoni  1
Affiliations
Review

The Use of Megamolecular Polysaccharide Sacran in Food and Biomedical Applications

Lisa Efriani Puluhulawa et al. Molecules. .

Abstract

Natural polymer is a frequently used polymer in various food applications and pharmaceutical formulations due to its benefits and its biocompatibility compared to synthetic polymers. One of the natural polymer groups (i.e., polysaccharide) does not only function as an additive in pharmaceutical preparations, but also as an active ingredient with pharmacological effects. In addition, several natural polymers offer potential distinct applications in gene delivery and genetic engineering. However, some of these polymers have drawbacks, such as their lack of water retention and elasticity. Sacran, one of the high-molecular-weight natural polysaccharides (megamolecular polysaccharides) derived from Aphanothece sacrum (A. sacrum), has good water retention and elasticity. Historically, sacran has been used as a dietary food. Moreover, sacran can be applied in biomedical fields as an active material, excipient, and genetic engineering material. This article discusses the characteristics, extraction, isolation procedures, and the use of sacran in food and biomedical applications.

Keywords: Aphanothece sacrum; polysaccharide; sacran.

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Conflict of interest statement

The authors have declared no conflict of interest.

Figures

Figure 1
Figure 1
Graphic of total articles used by year.
Figure 2
Figure 2
Scheme of sacran extraction process.
Figure 3
Figure 3
Structure of sacran [46].
See this image and copyright information in PMC

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