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Review
. 2021 Jun 8;22(12):6206.
doi: 10.3390/ijms22126206.

Anti-Pigmentary Natural Compounds and Their Mode of Action

Kyuri Kim  1 , YoonJung Huh  1 , Kyung-Min Lim  1
Affiliations
Review

Anti-Pigmentary Natural Compounds and Their Mode of Action

Kyuri Kim et al. Int J Mol Sci. .

Abstract

Hyper-activated melanocytes are the major cause of skin hyper-pigmentary disorders, such as freckles and melasma. Increasing efforts have been made to search for materials with depigmenting activity to develop functional cosmetics. As a result, numerous materials have been reported to have depigmenting activity but some of them are known to cause unwanted side effects. Consequently, anti-pigmentary natural compounds without concern of toxicity are in great demand. Virtually all sorts of natural sources have been investigated to find anti-pigmentary natural compounds. This review summarizes recently reported anti-pigmentary natural compounds and their mode of action from the ocean, plants, and bacteria.

Keywords: Tyrosinase; melanogenesis; natural compound; skin pigmentation.

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Conflict of interest statement

The authors declare no conflict of interest.

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