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. 2021 Jun 23;13(7):2159.
doi: 10.3390/nu13072159.

Dietary Fibre Intervention for Gut Microbiota, Sleep, and Mental Health in Adults with Irritable Bowel Syndrome: A Scoping Review

Ran Yan  1   2 , Lesley Andrew  1   2 , Evania Marlow  1 , Kanita Kunaratnam  1   2 , Amanda Devine  1   2 , Ian C Dunican  1 , Claus T Christophersen  1   3   4
Affiliations

Dietary Fibre Intervention for Gut Microbiota, Sleep, and Mental Health in Adults with Irritable Bowel Syndrome: A Scoping Review

Ran Yan et al. Nutrients. .

Abstract

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder affecting 4-5% of the global population. This disorder is associated with gut microbiota, diet, sleep, and mental health. This scoping review therefore aims to map existing research that has administrated fibre-related dietary intervention to IBS individuals and reported outcomes on at least two of the three following themes: gut microbiota, sleep, and mental health. Five digital databases were searched to identify and select papers as per the inclusion and exclusion criteria. Five articles were included in the assessment, where none reported on all three themes or the combination of gut microbiota and sleep. Two studies identified alterations in gut microbiota and mental health with fibre supplementation. The other three studies reported on mental health and sleep outcomes using subjective questionnaires. IBS-related research lacks system biology-type studies targeting gut microbiota, sleep, and mental health in patients undergoing diet intervention. Further IBS research is required to explore how human gut microbiota functions (such as short-chain fatty acids) in sleep and mental health, following the implementation of dietary pattern alteration or component supplementation. Additionally, the application of objective sleep assessments is required in order to detect sleep change with more accuracy and less bias.

Keywords: FODMAP; IBS; dietary fibre; gut microbiota; mental health; short-chain fatty acid; sleep.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
PRISMA flow chart of articles identification and inclusion.
Figure 2
Figure 2
A relative hierarchy in order of sleep assessment methods.
See this image and copyright information in PMC

References

    1. Quigley E.M., Fried M., Gwee K.A., Khalif I., Hungin A.P., Lindberg G., Abbas Z., Fernandez L.B., Bhatia S.J., Schmulson M., et al. World Gastroenterology Organisation Global Guidelines Irritable Bowel Syndrome: A Global Perspective Update September 2015. J. Clin. Gastroenterol. 2016;50:704–713. doi: 10.1097/MCG.0000000000000653. - DOI - PubMed
    1. Lacy B.E., Ayyagari R., Guerin A., Lopez A., Shi S., Luo M. Factors associated with more frequent diagnostic tests and procedures in patients with irritable bowel syndrome. Therap. Adv. Gastroenterol. 2019;12 doi: 10.1177/1756284818818326. - DOI - PMC - PubMed
    1. Lovell R.M., Ford A.C. Global prevalence of and risk factors for irritable bowel syndrome: A meta-analysis. Clin. Gastroenterol. Hepatol. 2012;10:712–721. doi: 10.1016/j.cgh.2012.02.029. - DOI - PubMed
    1. Palsson O.S., Whitehead W., Tornblom H., Sperber A.D., Simren M. Prevalence of Rome IV Functional Bowel Disorders Among Adults in the United States, Canada, and the United Kingdom. Gastroenterology. 2020;158:1262–1273. doi: 10.1053/j.gastro.2019.12.021. - DOI - PubMed
    1. Sperber A.D., Bangdiwala S.I., Drossman D.A., Ghoshal U.C., Simren M., Tack J., Whitehead W.E., Dumitrascu D.L., Fang X., Fukudo S., et al. Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study. Gastroenterology. 2021;160:99–114. doi: 10.1053/j.gastro.2020.04.014. - DOI - PubMed

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