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Review
. 2021 Jun 18;13(12):3048.
doi: 10.3390/cancers13123048.

Cancer and Pregnancy: A Comprehensive Review

Roxana Schwab  1 , Katharina Anic  1 , Annette Hasenburg  1
Affiliations
Review

Cancer and Pregnancy: A Comprehensive Review

Roxana Schwab et al. Cancers (Basel). .

Abstract

Cancer diagnosis and treatment in pregnant women is a challenging situation. A multidisciplinary network of specialists is required to guide both, the expecting mother and the unborn child through the diagnostic workup and the cytotoxic therapy, by balancing the respective risks and benefits. Tumor entity, stage, biology and gestational week at diagnosis determine the appropriate approach. As premature delivery emerged as one of the main risk factors for adverse long-term outcome of the progeny, it should be avoided, if reasonable from the oncological perspective. This article offers a comprehensive review with respect to the various aspects of cancer in pregnancy.

Keywords: cancer; diagnostic procedures; fetal outcome; pregnancy; therapeutic procedures.

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Conflict of interest statement

R.S. Honoraria: Roche Pharma AG, AstraZeneca, Streamedup!GmbH, A.H. Honoraria: AstraZeneca; Celgen; MedConcept GmbH, Med update GmbH; Medicultus; Pfizer; Promedicis GmbH; Softconsult; Roche Pharma AG; Streamedup!GmbH; Tesaro Bio Germany GmbH, LEO Pharma. Ad Board: PharmaMar; Promedicis GmbH; Roche Pharma AG; Tesaro Bio Germany GmbH, AstraZeneca, LEO Pharma, MSD Sharp&Dohme GmbH.

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