Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Jun 16;10(6):1395.
doi: 10.3390/foods10061395.

The Epic of In Vitro Meat Production-A Fiction into Reality

Affiliations
Review

The Epic of In Vitro Meat Production-A Fiction into Reality

Balamuralikrishnan Balasubramanian et al. Foods. .

Abstract

Due to a proportionally increasing population and food demands, the food industry has come up with wide innovations, opportunities, and possibilities to manufacture meat under in vitro conditions. The amalgamation of cell culture and tissue engineering has been the base idea for the development of the synthetic meat, and this has been proposed to be a pivotal study for a futuristic muscle development program in the medical field. With improved microbial and chemical advancements, in vitro meat matched the conventional meat and is proposed to be eco-friendly, healthy, nutrient rich, and ethical. Despite the success, there are several challenges associated with the utilization of materials in synthetic meat manufacture, which demands regulatory and safety assessment systems to manage the risks associated with the production of cultured meat. The role of 3D bioprinting meat analogues enables a better nutritional profile and sensorial values. The integration of nanosensors in the bioprocess of culture meat eased the quality assessment throughout the food supply chain and management. Multidisciplinary approaches such as mathematical modelling, computer fluid dynamics, and biophotonics coupled with tissue engineering will be promising aspects to envisage the future prospective of this technology and make it available to the public at economically feasible rates.

Keywords: 3D bioprinting; acceptance; cultured meat; eco-friendly; meat substitute; multidisciplinary approaches; nanosensors; stem cells; technical challenges.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Figure 1
Figure 1
A pipeline for the production of illustrating the common stages involved in the production of a cultured meat product.
Figure 2
Figure 2
An illustration of the acceptance of in vitro meat across the three religions [18].
Figure 3
Figure 3
The agenda underpinning the promotion and acceptance of artificial meat.
Figure 4
Figure 4
The trans-disciplinary application of 3D bioprinting in in vitro culture meat technique.

References

    1. Di Marco M., Baker M.L., Daszak P., De Barro P., Eskew E.A., Godde C.M., Harwood T.D., Herrero M., Hoskins A.J., Johnson E., et al. Sustainable development must account for pandemic risk. Proc. Natl. Acad. Sci. USA. 2020;117:3888–3892. doi: 10.1073/pnas.2001655117. - DOI - PMC - PubMed
    1. The Guardian. [(accessed on 23 February 2021)];2020 Available online: https://www.theguardian.com/environment/2020/dec/02/no-kill-lab-grown-me....
    1. Pandurangan M., Kim D.H. A novel approach for in vitro meat production. Appl. Microbiol. Biotechnol. 2015;99:5391–5395. doi: 10.1007/s00253-015-6671-5. - DOI - PubMed
    1. Choudhury D., Tseng T.W., Swartz E. The business of cultured meat. Trends Biotechnol. 2020;38:573–577. doi: 10.1016/j.tibtech.2020.02.012. - DOI - PubMed
    1. Bonny S.P.F., Gardner G.E., Pethick D.W., Hocquette J. What is artificial meat and what does it mean for the future of the meat industry? J. Integr. Agric. 2015;14:255–263. doi: 10.1016/S2095-3119(14)60888-1. - DOI

LinkOut - more resources