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Observational Study
. 2021 Jun 30;13(7):2276.
doi: 10.3390/nu13072276.

Evolution of Nutritional Status after Early Nutritional Management in COVID-19 Hospitalized Patients

Dorothée Bedock  1 , Julie Couffignal  1 , Pierre Bel Lassen  1   2 , Leila Soares  1 , Alexis Mathian  3 , Jehane P Fadlallah  3 , Zahir Amoura  3 , Jean-Michel Oppert  1 , Pauline Faucher  1
Affiliations
Observational Study

Evolution of Nutritional Status after Early Nutritional Management in COVID-19 Hospitalized Patients

Dorothée Bedock et al. Nutrients. .

Abstract

Background & Aims: SARS-CoV2 infection is associated with an increased risk of malnutrition. Although there are numerous screening and nutritional management protocols for malnutrition, only few studies have reported nutritional evolution after COVID-19. The objectives of this study were to describe the evolution of nutritional parameters between admission and 30 days after hospital discharge, and to determine predictive factors of poor nutritional outcome after recovery in adult COVID-19 patients. Methods: In this observational longitudinal study, we report findings after discharge in 91 out of 114 patients initially admitted for COVID-19 who received early nutritional management. Nutritional status was defined using GLIM criteria and compared between admission and day 30 after discharge. Baseline predictors of nutritional status at day 30 were assessed using logistic regression. Results: Thirty days after discharge, 28.6% of patients hospitalized for COVID-19 were malnourished, compared to 42.3% at admission. Half of malnourished patients (53%) at admission recovered a normal nutritional status after discharge. Weight trajectories were heterogeneous and differed if patients had been transferred to an intensive care unit (ICU) during hospitalization (p = 0.025). High oxygen requirement during hospitalization (invasive ventilation p = 0.016 (OR 8.3 [1.6-61.2]) and/or oxygen therapy over 5 L/min p = 0.021 (OR 3.2 [1.2-8.9]) were strong predictors of malnutrition one month after discharge. Conclusions: With early nutritional management, most patients hospitalized for COVID-19 improved nutritional parameters after discharge. These findings emphasize the importance of nutritional care in COVID-19 patients hospitalized in medicine departments, especially in those transferred from ICU.

Keywords: COVID-19; SARS-Cov2; albumin; malnutrition; nutritional management; pneumonia.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Figure 1
Figure 1
Individual weight change (%) in COVID-19 patients between usual weight, hospital admission and 30 days after discharge.
Figure 2
Figure 2
Mean weight change (%) in COVID-19 patients depending on whether patients were transferred to ICU or not during hospital stay.
Figure 3
Figure 3
Evolution of nutritional status according to GLIM criteria between admission and 30 days after hospital discharge in COVID-19 patients.
See this image and copyright information in PMC

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