A call for better understanding the role of albumin in mediating VE-cadherin phosphorylation and endothelial barrier dysfunction in septic patients
- PMID: 34210346
- PMCID: PMC8252191
- DOI: 10.1186/s13054-021-03637-y
A call for better understanding the role of albumin in mediating VE-cadherin phosphorylation and endothelial barrier dysfunction in septic patients
Conflict of interest statement
The authors declare that they have no competing interests.
Comment on
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Endothelial damage in septic shock patients as evidenced by circulating syndecan-1, sphingosine-1-phosphate and soluble VE-cadherin: a substudy of ALBIOS.Crit Care. 2021 Mar 19;25(1):113. doi: 10.1186/s13054-021-03545-1. Crit Care. 2021. PMID: 33741039 Free PMC article. Clinical Trial.
References
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- Piotti A, Novelli D, Meessen JMTA, Ferlicca D, Coppolecchia S, Marino A, et al. Endothelial damage in septic shock patients as evidenced by circulating syndecan-1, sphingosine-1-phosphate and soluble VE-cadherin: a substudy of ALBIOS. Crit Care. 2021;25:113. doi: 10.1186/s13054-021-03545-1. - DOI - PMC - PubMed
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- Gong P, Angelini DJ, Yang S, Xia G, Cross AS, Mann D, et al. TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia. J Biol Chem. 2008;283:13437–13449. doi: 10.1074/jbc.M707986200. - DOI - PMC - PubMed
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