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Editorial
. 2021 Jul 1;22(1):196.
doi: 10.1186/s13059-021-02395-y.

CLIMB-COVID: continuous integration supporting decentralised sequencing for SARS-CoV-2 genomic surveillance

Samuel M Nicholls  1 , Radoslaw Poplawski  1 , Matthew J Bull  2 , Anthony Underwood  3   4 , Michael Chapman  5 , Khalil Abu-Dahab  3   4 , Ben Taylor  3   4 , Rachel M Colquhoun  6 , Will P M Rowe  1 , Ben Jackson  6 , Verity Hill  6 , Áine O'Toole  6 , Sara Rey  2 , Joel Southgate  7 , Roberto Amato  8 , Rich Livett  8 , Sónia Gonçalves  8 , Ewan M Harrison  8   9   10 , Sharon J Peacock  9 , David M Aanensen  3   4 , Andrew Rambaut  6 , Thomas R Connor  2   7   11 , Nicholas J Loman  12 ; COVID-19 Genomics UK (COG-UK) Consortium
Affiliations
Free PMC article
Editorial

CLIMB-COVID: continuous integration supporting decentralised sequencing for SARS-CoV-2 genomic surveillance

Samuel M Nicholls et al. Genome Biol. .
Free PMC article

Abstract

In response to the ongoing SARS-CoV-2 pandemic in the UK, the COVID-19 Genomics UK (COG-UK) consortium was formed to rapidly sequence SARS-CoV-2 genomes as part of a national-scale genomic surveillance strategy. The network consists of universities, academic institutes, regional sequencing centres and the four UK Public Health Agencies. We describe the development and deployment of CLIMB-COVID, an encompassing digital infrastructure to address the challenge of collecting and integrating both genomic sequencing data and sample-associated metadata produced across the COG-UK network.

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References

    1. Gigascience. 2022 Feb 16;11: - PubMed
    1. Cell. 2021 Jan 7;184(1):64-75.e11 - PubMed
    1. Bioinformatics. 2012 Oct 1;28(19):2520-2 - PubMed
    1. Science. 2021 Feb 12;371(6530):708-712 - PubMed
    1. Euro Surveill. 2017 Mar 30;22(13): - PubMed

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