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. 2021 Jun 21;11(4):470-472.
doi: 10.1080/20009666.2021.1921908.

Resolution of pulmonary artery thrombosis in patients with moderate COVID-19 disease

Grazia Zanframundo  1 , Alessandro Graziani  1 , Caroli Barbara  1 , Palmese Francesco  1 , Minguzzi Maria Teresa  2 , Cataleta Cristian  3 , Graziani Pierluigi  4 , Domenicali Ludovico  5
Affiliations

Resolution of pulmonary artery thrombosis in patients with moderate COVID-19 disease

Grazia Zanframundo et al. J Community Hosp Intern Med Perspect. .

Abstract

Novel Coronavirus disease (COVID-19) has been widely described as the cause for a proinflammatory and hypercoagulable state. The inflammatory process involving the alveolar vascular endothelium in the respiratory system, is a determining factor for the onset of primary Pulmonary Artery Thrombosis (PAT) even in patients with heparin prophylactic treatment. Little is known about the efficacy of the anticoagulant therapy during the course of PAT caused by COVID-19. In this paper we describe the results obtained in patients with moderate COVID-19 disease, previously threated with prophylactic enoxaparin, who then received full Anticoagulant treatment after diagnosis of PAT. After three months Computed Tomography Pulmonary Angiography demonstrated a complete resolution of the vascular obstructive lesions in all patients, while all the coagulation tests were normal.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
(a) Pulmonary artery thrombosis (red arrows). (b) complete resolution of the thrombosisCTPA documented the complete resolution of the arterial thrombotic lesions in all patients
See this image and copyright information in PMC

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