"Eyeing" corneal stem cell identity, dynamics, and compartmentalization
- PMID: 34214435
- DOI: 10.1016/j.stem.2021.06.001
"Eyeing" corneal stem cell identity, dynamics, and compartmentalization
Abstract
The mammalian cornea is maintained by the lifelong self-replenishing activity of its stem cells. In this issue of Cell Stem Cell, Altshuler et al. (2021) and Farrelly et al. (2021) identify two stem cell populations with diverse function and genetic signature, one "active" and one "quiescent," that support corneal health.
Copyright © 2021 Elsevier Inc. All rights reserved.
Comment on
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Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing.Cell Stem Cell. 2021 Jul 1;28(7):1248-1261.e8. doi: 10.1016/j.stem.2021.04.003. Epub 2021 May 12. Cell Stem Cell. 2021. PMID: 33984282 Free PMC article.
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Two-photon live imaging of single corneal stem cells reveals compartmentalized organization of the limbal niche.Cell Stem Cell. 2021 Jul 1;28(7):1233-1247.e4. doi: 10.1016/j.stem.2021.02.022. Epub 2021 May 12. Cell Stem Cell. 2021. PMID: 33984283 Free PMC article.
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