A growing genetic tree in the soil of prostate
- PMID: 34214437
- DOI: 10.1016/j.stem.2021.06.002
A growing genetic tree in the soil of prostate
Abstract
In this issue of Cell Stem Cell, Grossmann et al. (2021) reconstructed the developmental history of the prostate gland in a 59-year-old male by 3D tracking of somatic mutations across 319 micro-dissected specimens. It provides a genetic picture of how the human prostate gland is shaped during embryogenesis, puberty, and adult life.
Copyright © 2021 Elsevier Inc. All rights reserved.
Comment on
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Development, maturation, and maintenance of human prostate inferred from somatic mutations.Cell Stem Cell. 2021 Jul 1;28(7):1262-1274.e5. doi: 10.1016/j.stem.2021.02.005. Epub 2021 Mar 2. Cell Stem Cell. 2021. PMID: 33657416 Free PMC article.
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