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Review
. 2021 Aug;47(3):513-530.
doi: 10.1016/j.rdc.2021.04.012. Epub 2021 Jun 10.

Treatment Update in Systemic Lupus Erythematous

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Review

Treatment Update in Systemic Lupus Erythematous

Alberta Y Hoi et al. Rheum Dis Clin North Am. 2021 Aug.

Abstract

The recent updates on treatment recommendations for the management of systemic lupus erythematous have provided greater clarity in the way existing anti-inflammatory and immunomodulatory drugs are used, in treating disease activity, preventing flares, and reducing irreversible organ damage and toxicity arising from the treatments themselves. Novel therapies will provide more options in the armamentarium for treating this complex disease, but ongoing studies are needed to improve understanding of the optimal treatment algorithm to maintain quality of life and improve survival for patients.

Keywords: Anifrolumab; Belimumab; Euro-lupus; Lupus; Lupus low disease activity state; Lupus nephritis; Mycophenolate; Treatment target.

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