Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jun;191(3):1453-1455.
doi: 10.1007/s11845-021-02701-4. Epub 2021 Jul 2.

Peripheral blood natural killer cell depletion is associated with severe pneumonia in coronavirus disease-2019 (COVID-19)

Ricardo Garcia-Muñoz  1 , Jesus Feliu  2 , Judit Anton-Remirez  3 , Luis Metola  4 , Enrique Sosa-Campos  5 , Maria-Pilar Sanz  6 , Giovanna Farfan  2 , Eztizen Labrador-Sanchez  7 , Valvanera Ibarra  4 , Jose-Luis Peña  8 , Ana Pascual  9 , María-Jesús Hermosa  10 , Miriam Blasco  11 , Lorena Llerena-Garcia  11 , María-José Najera  2 , José Antonio Oteo  4
Affiliations

Peripheral blood natural killer cell depletion is associated with severe pneumonia in coronavirus disease-2019 (COVID-19)

Ricardo Garcia-Muñoz et al. Ir J Med Sci. 2022 Jun.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
NK cells according to pneumonia severity
Fig. 2
Fig. 2
NK cells > or < 100 according to pneumonia severity pneumonia severity. In the peripheral blood, the normal range of NK cells in adults is 85–505 cells/mcL (4)
See this image and copyright information in PMC

References

    1. Li MY, Li L, Zhang Y, Wang XS (2020) Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues. Infect Dis Poverty. 28;9(1):45 - PMC - PubMed
    1. Totura AL, Baric RS. SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon. Curr Opin Virol. 2012;2(3):264–275. doi: 10.1016/j.coviro.2012.04.004. - DOI - PMC - PubMed
    1. Vivier E, Tomasello E, Baratin M, et al. Functions of natural killer cells. Nat Immunol. 2008;9(5):503–510. doi: 10.1038/ni1582. - DOI - PubMed
    1. Rich RR, Fleisher TA, Shearer WT et al (eds) (2019) Clinical immunology. Principles and practice. 4th edn. Elsevier Saunders 860–873, 716–727
    1. Tay MZ, Poh CM, Rénia L, et al. The trinity of COVID-19: immunity, inflammation and intervention. Nat Rev Immunol. 2020;20(6):363–374. doi: 10.1038/s41577-020-0311-8. - DOI - PMC - PubMed

LinkOut - more resources