Anterior uveal fungal abscess in an HIV positive patient

Abstract

Endogenous endophthalmitis (EE) accounts for approximately 2% to 8% of all cases of endophthalmitis. Candida albicans abscesses in the iris and ciliary body are a rare form of presentation, with only 3 cases reported up until now. The case is presented of a 27-year-old patient with an elevated lesion in the iris at the temporal zone of the left eye, with hypopyon, pupil membrane, and 4+ cells in the anterior chamber. Tests for syphilis and HIV were positive, and were associated with extraocular manifestations of secondary syphilis. Treatment with intravenous penicillin and HAART therapy were started, but the clinical course worsened after 7 days. Pars plana vitrectomy and an abscess aspiration were performed, and the intraocular fluids and the purulent content were sent for microbiological examination. Cultures were positive for Candida albicans. The case is presented of an anterior uveal abscess by Candida albicans in an HIV-positive patient not previously reported in the literature.

Keywords: Candida; Cándida; Endoftalmitis del VIH; Endoftalmitis endógena; Endoftalmitis fúngica; Endoftalmitis micótica; Endogenous endophthalmitis; Fluconazol; Fluconazole; Fungal endophthalmitis; HIV endophthalmitis; Mycotic endophthalmitis.