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Randomized Controlled Trial
. 2021 Oct;48(10):1293-1301.
doi: 10.1111/jcpe.13518. Epub 2021 Jul 23.

Clinical evaluation of xenogeneic collagen matrix versus free gingival grafts for keratinized mucosa augmentation around dental implants: A randomized controlled clinical trial

Jia-Ping Huang  1 , Jia-Mei Liu  2 , Yan-Min Wu  3 , Anna Dai  1 , Hua-Jiao Hu  3 , Fu-Ming He  1 , Qian-Ming Chen  1 , Xiao-Jun Li  1 , Ping Sun  1 , Pei-Hui Ding  1   3
Affiliations
Randomized Controlled Trial

Clinical evaluation of xenogeneic collagen matrix versus free gingival grafts for keratinized mucosa augmentation around dental implants: A randomized controlled clinical trial

Jia-Ping Huang et al. J Clin Periodontol. 2021 Oct.

Abstract

Aim: To evaluate the outcomes of an apically repositioned flap (ARF) plus xenogeneic collagen matrix (XCM) in augmenting keratinized mucosa width (KMW) around dental implants when compared with ARF plus free gingival grafts (FGG).

Materials and methods: Twenty-six participants with at least one site with KMW ≤2 mm were randomized into FGG or XCM group. Clinical examinations were performed at baseline and at 2 and 6 months after surgery, including KMW, keratinized mucosa thickness, gingival index (GI), and probing depth (PD). Post-operative pain and patient satisfaction were also evaluated.

Results: At 6 months, FGG attained a greater increase of KMW and thicker mucosa than XCM (4.1 ± 1.6 mm vs. 1.8 ± 1.0 mm, p < .001; 1.7 ± 0.6 mm vs. 1.2 ± 0.3 mm, p < .01). Regarding GI, PD, post-operative pain, aesthetic outcomes, and patient satisfaction, no significant difference could be detected. Moreover, the operation time of XCM group was shorter (60 ± 9 min vs. 39 ± 8 min, p < .001).

Conclusions: FGG could result in greater increase of KMW than XCM, though both could increase KMW, maintain peri-implant health, and attain comparable aesthetic outcomes. The use of XCM was associated with reduced operation time.

Keywords: collagen matrix; dental implants; free gingival graft; keratinized mucosa; randomized controlled trial.

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References

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