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. 2021 Sep;56(9):2918-2924.
doi: 10.1002/ppul.25558. Epub 2021 Jul 16.

EVALI versus MIS-C, one more overlapping diagnosis to consider

Diego A Cruz-Vidal  1 , Eric S Mull  2 , Jeanette Taveras  1 , Richard Shell  2 , Garrett W Hunt  1 , Brian Fowler  1 , Rebecca Wallihan  1 , Guliz Erdem  1
Affiliations

EVALI versus MIS-C, one more overlapping diagnosis to consider

Diego A Cruz-Vidal et al. Pediatr Pulmonol. 2021 Sep.

Abstract

We describe six teenagers presenting with fever and severe abdominal symptoms admitted with concerns for multisystem inflammatory syndrome in children (MIS-C). Laboratory evaluation revealed elevated markers of inflammation, lymphopenia, and increased D-dimers. Imaging studies revealed multifocal airspace disease and ground-glass opacities. SARS-CoV-2 polymerase chain reaction and serologies were negative. All patients reported a history of vaping, prompting E-cigarette, or vaping, product use-associated lung injury (EVALI) diagnosis. MIS-C has overlapping clinical and laboratory features highlighting the added challenge of diagnosing EVALI during the COVID-19 pandemic. Keywords COVID-19 pandemic, EVALI, MIS-C.

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References

REFERENCES

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    1. Centers for Disease Control and Prevention. Multisystemic Inflammatory Syndrome in Children (MIS-C) associated with Coronavirus Disease 2019 (COVID-19). CDC Health Alert Network; 2020. https://emergency.cdc.gov/han/2020/han00432.asp. Accessed February 8, 2021.
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