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Case Reports
. 2021 Mar 20;10(3):201-206.
doi: 10.1007/s13691-021-00479-x. eCollection 2021 Jul.

Definitive radiotherapy for secondary esophageal cancer after allogeneic hematopoietic stem cell transplantation

Aki Ino  1 , Katsuyuki Sakanaka  1 , Hiroyuki Inoo  1 , Yuichi Ishida  1 , Junya Kanda  2 , Takashi Mizowaki  1
Affiliations
Case Reports

Definitive radiotherapy for secondary esophageal cancer after allogeneic hematopoietic stem cell transplantation

Aki Ino et al. Int Cancer Conf J. .

Abstract

The reports for secondary esophageal cancer treated by radiotherapy or chemoradiotherapy is few, however they potentially yield a cure for esophageal cancer. We report a case of definitive radiotherapy for a patient with secondary locally advanced unresectable esophageal cancer after hematopoietic stem cell transplantation for acute myeloid leukemia. Definitive radiotherapy for the current patient was completed with acceptable toxicity despite the poor general condition with long-term chronic graft-versus-host disease. Radiotherapy may be the definitive treatment for this population unfit for concurrent chemotherapy or surgery.

Keywords: Esophageal cancer; Hematopoietic stem cell transplantation; Radiotherapy; Secondary malignancy.

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Conflict of interest statement

Conflict of interestThe authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Computed tomography images of primary esophageal tumor (a), left gastric lymph nodal enlargement (b), paratracheal (c), and esophagogastroduodenoscopy image of primary esophageal tumor (d) before radiotherapy
Fig. 2
Fig. 2
Dose distributions of axial images in primary esophageal tumor level (a), paratracheal level (b), and left gastric lymph level (c), and coronal image (d)
Fig. 3
Fig. 3
Computed tomography images of the primary esophageal tumor (a), left gastric lymph nodal metastasis (b) and paratracheal (c), and esophagogastroduodenoscopy image of primary esophageal tumor (d) after 5 years of radiotherapy
See this image and copyright information in PMC

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