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. 2021 Jun 17:8:670034.
doi: 10.3389/fmed.2021.670034. eCollection 2021.

Effect of Cost-Related Medication Non-adherence Among Older Adults With Medication Therapy Management

Weiwei Zhang  1 , Gang Lv  2 , Xiaomo Xiong  3 , Minghui Li  4
Affiliations

Effect of Cost-Related Medication Non-adherence Among Older Adults With Medication Therapy Management

Weiwei Zhang et al. Front Med (Lausanne). .

Abstract

Background: Medication therapy management (MTM) was established by the Center for Medicare and Medicaid Services (CMS) with the aim to improve medication adherence. However, the national prevalence of cost-related medication non-adherence (CRN) is still unknown and there is a literature gap in the association between MTM services and CRN. Methods: A cross-sectional study was conducted. A nationally representative study sample from Medicare Current Beneficiary Surveys (MCBS) was used. Survey sampling weights were applied for national estimates of CRN. Weighted multivariable logistic regressions controlling for covariates were conducted to investigate the effect of the MTM on the CRN. Results: The study identified 1,549 MTM-eligible beneficiaries. The prevalence of CRN was higher in MTM-eligible individuals than in non-MTM eligible individuals (24.14 vs. 13.44%; P < 0.001). According to the results of multivariable logistic regressions, we found that MTM eligibility was significantly associated with a higher prevalence of CRN (OR: 1.59; 95% CI: 1.28-1.96). Additionally, some other variables such as health status, with or without low-income subsidy are also associated with CRN. Conclusions: Our findings suggest that the prevalence of CRN in MTM-eligible beneficiaries was higher than in non-MTM eligible beneficiaries. Further studies with the longitudinal design are warranted to clarify the relationship between MTM and CRN. Alternative strategies to improve CRN should be considered in future Medicare Part D Enhanced MTM Models.

Keywords: Medicare beneficiaries; Medicare part D; cost-related medication non-adherence; medication therapy management; pharmacist.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Forest plot for odds ratio and 95% CI of regression for cost-related medication non-adherence among the study group. MTM, medication therapy management; CRN, cost-related non-adherence; BMI, body mass index; ADL, activities of daily living; LIS, low-income subsidy; CI, confidence interval; LL, lower limit; UL, upper limit. *P < 0.05.
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References

    1. Centers for Medicare and Medicaid Service (CMS) H . Medicare program; medicare prescription drug benefit, Final Rule. Fed Regist. (2005) 70:4193–585. - PubMed
    1. Pellegrino AN, Martin MT, Tilton JJ, Touchette DR. Medication therapy management services: definitions and outcomes. Drugs. (2009) 69:393–406. 10.2165/00003495-200969040-00001 - DOI - PubMed
    1. (CMS) CfMaMS. Medication Therapy Management (2021) [updated 2021 May 4th]. Available online at: https://www.cms.gov/Medicare/Prescription-Drug-Coverage/PrescriptionDrug... (accessed May 10, 2021).
    1. American Pharmacists A National Association of Chain Drug Stores F . Medication therapy management in pharmacy practice: core elements of an MTM service model (version 2.0). J Am Pharm Assoc. (2008) 48:341–53. 10.1331/JAPhA.2008.08514 - DOI - PubMed
    1. Prevention CfDCa. Community Pharmacists and Medication Therapy Management. Available online at: https://www.cdc.gov/dhdsp/pubs/docs/Best_Practice_Guide_MTM_508.pdf (accessed January 18, 2018).