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Case Reports
. 2021 May 25;8(3):314-316.
doi: 10.14744/nci.2020.97720. eCollection 2021.

Gastric hepatoid carcinoma: Report of a case

Metin Leblebici  1 , Cem Ilgın Erol  1 , Ozgur Ekinci  1 , Nesrin Gunduz  2 , Furkan Kilic  1 , Mehmet Acar  1 , Tunc Eren  1 , Rabia Burcin Girgin  3 , Orhan Alimoglu  1
Affiliations
Case Reports

Gastric hepatoid carcinoma: Report of a case

Metin Leblebici et al. North Clin Istanb. .

Abstract

Gastric hepatoid carcinoma (GHC) is a rare type of gastric cancer with a tendency to have poor prognosis and metastasize to the liver. GHCs generally show histopathologically hepatocellular differentiation and secrete alpha fetoprotein (AFP). AFP production can occur in cancers originating from the embryologically similar liver, gastrointestinal tract, and yolk sac and often metastasizes to the liver. Although GHC is aggressive, it may not always cause liver metastasis and may invade into the other abdominal organs by direct contact. In this article, we present a case of locally advanced GHC with high AFP levels.

Keywords: Alpha fetoprotein protein; gastric cancer; gastric diseases; human.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

FIGURE 1
FIGURE 1
Image of positron emission tomography computed tomography, locally advanced gastric hepatoid carcinoma (SUDmax: 18.6).
FIGURE 2
FIGURE 2
Image of positron emission tomography computed tomography, regression after neoadjuvant therapy locally advanced gastric hepatoid carcinoma (SUDmax: 12.7).
See this image and copyright information in PMC

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