Isn't it time to stop calling preimplantation embryos "mosaic"?

Richard J Paulson¹, Nathan R Treff^{2

3}

Affiliations

¹ Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Keck School of Medicine, University of Southern California, Los Angeles, California.
² Genomic Prediction, North Brunswick, New Jersey.
³ Rutgers University-Robert Wood Johnson Medical School, Department of Obstetrics, Gynecology, and Reproductive Sciences, New Brunswick, New Jersey.

PMID: 34223234
PMCID: PMC8244277
DOI: 10.1016/j.xfre.2020.10.009

Editorial

Isn't it time to stop calling preimplantation embryos "mosaic"?

Richard J Paulson et al. F S Rep. 2020.

. 2020 Nov 4;1(3):164-165.

doi: 10.1016/j.xfre.2020.10.009. eCollection 2020 Dec.

Authors

Richard J Paulson¹, Nathan R Treff^{2

3}

Affiliations

¹ Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Keck School of Medicine, University of Southern California, Los Angeles, California.
² Genomic Prediction, North Brunswick, New Jersey.
³ Rutgers University-Robert Wood Johnson Medical School, Department of Obstetrics, Gynecology, and Reproductive Sciences, New Brunswick, New Jersey.

PMID: 34223234
PMCID: PMC8244277
DOI: 10.1016/j.xfre.2020.10.009

No abstract available

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References

1. Practice Committee and Genetic Counseling Professional Group (GCPG) of the American Society for Reproductive Medicine Clinical management of mosaic results from preimplantation genetic testing for aneuploidy (PGT-A) of blastocysts: a committee opinion. Fertil Steril. 2020;114:246–254. - PubMed
1. Viotti M., Victor A., Barne S.F., Zouves C., Besser A.G., Grifo J.A. New insights from one thousand mosaic embryo transfers: features of mosaicism dictating rates of implantation, spontaneous abortion, and neonate health. Fertil Steril. 2020;114:e1–e2.
1. Kahraman S., Cetinkaya M., Yuksel B., Yesil M., Pirkevi Cetinkaya C. The birth of a baby with mosaicism resulting from a known mosaic embryo transfer: a case report. Hum Reprod. 2020;35:727–733. - PMC - PubMed
1. Ottolini C.S., Kitchen J., Xanthopoulou L., Gordon T., Summers M.C., Handyside A.H. Tripolar mitosis and partitioning of the genome arrests human preimplantation development in vitro. Sci Rep. 2017;7:9744. - PMC - PubMed
1. Huang A., Adusumalli J., Patel S., Liem J., Williams J., 3rd, Pisarska M.D. Prevalence of chromosomal mosaicism in pregnancies from couples with infertility. Fertil Steril. 2009;91:2355–2360. - PubMed

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Isn't it time to stop calling preimplantation embryos "mosaic"?

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Isn't it time to stop calling preimplantation embryos "mosaic"?

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