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Comment
. 2021 Sep;17(9):577.
doi: 10.1038/s41584-021-00653-8.

Combining TNF blockade with immune checkpoint inhibitors in patients with cancer

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Comment

Combining TNF blockade with immune checkpoint inhibitors in patients with cancer

Anne Montfort et al. Nat Rev Rheumatol. 2021 Sep.
No abstract available

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References

    1. Montfort, A. et al. The TNF paradox in cancer progression and immunotherapy. Front. Immunol. 10, 1818 (2019). - DOI
    1. Balkwill, F. Tumour necrosis factor and cancer. Nat. Rev. Cancer 9, 361–371 (2009). - DOI
    1. Chen, A. Y., Wolchok, J. D. & Bass, A. R. TNF in the era of immune checkpoint inhibitors: friend or foe? Nat. Rev. Rheumatol. 17, 213–223 (2021). - DOI
    1. Bertrand, F. et al. TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma. Nat. Commun. 8, 2256 (2017). - DOI
    1. Perez-Ruiz, E. et al. Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy. Nature 569, 428–432 (2019). - DOI

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