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. 2021 Aug;51(8):681-693.
doi: 10.4070/kcj.2021.0029. Epub 2021 May 21.

Economic Burden of Heart Failure in Asian Countries with Different Healthcare Systems

Affiliations

Economic Burden of Heart Failure in Asian Countries with Different Healthcare Systems

Teerapat Yingchoncharoen et al. Korean Circ J. 2021 Aug.

Abstract

Background and objectives: Heart failure (HF) poses substantial economic burden, primarily driven by high hospitalization and mortality rates. This study aimed to understand the economic burden of HF in 4 Asian countries under varying healthcare systems.

Methods: This was a non-interventional, retrospective study conducted in South Korea, Taiwan, Thailand and Malaysia through medical chart review. Eligible patients included those who had either ≥1 hospitalization or ≥2 outpatient visits from January 1st to December 31st, 2014, and at least one year of follow-up. Resource use and direct healthcare costs (adjusted to 2015 USD) of HF were assessed. HF costs for subgroups stratified by age and sex were assessed.

Results: A total of 568 patients were recruited from South Korea (n=200), Taiwan (n=200), Thailand (n=100) and Malaysia (n=68). The proportion of patients hospitalized ranged from 20.0% to 93.5% (South Korea 20.0%, Thailand 49.0%, Malaysia 70.6%, and Taiwan 93.5%). The overall annual HF cost per patient was $2,357, $4,513, $3,513 and $1,443 in South Korea, Taiwan, Thailand, and Malaysia, respectively; hospitalized HF care costs were $10,714, $4,790, $7,181 and $1,776, respectively. The length of stay was more than 12.2 days except in Malaysia. No specific trend was observed in subgroup analysis.

Conclusions: In Asia, HF poses significant economic burden and hospitalization has emerged as the major cost driver among healthcare costs. A streamlined treatment strategy reducing hospitalization rate can minimize the economic burden.

Keywords: Cost of illness; Health care costs; Heart failure; Hospitalization; Length of stay.

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Conflict of interest statement

T.Y., T.C.W., D.J.C., O.T.K., H.B.L., and M.C.C report grants from Novartis. Any financial or other conflicts that could impact study conclusion does not exist.

Figures

Figure 1
Figure 1. Costs and resource use for hospitalized patients in four Asian countries.
LOS = length of stay.

References

    1. McMurray JJ, Adamopoulos S, Anker SD, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2012;33:1787–1847. - PubMed
    1. Ambrosy AP, Fonarow GC, Butler J, et al. The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries. J Am Coll Cardiol. 2014;63:1123–1133. - PubMed
    1. Lloyd-Jones DM, Larson MG, Leip EP, et al. Lifetime risk for developing congestive heart failure: the Framingham Heart Study. Circulation. 2002;106:3068–3072. - PubMed
    1. Sutherland K. Bridging the Quality Gap: Heart Failure. 1st ed. London: The Health Foundation; 2010. p. 111.
    1. Richard Hobbs FD. Clinical burden and health service challenges of chronic heart failure. Br J Gen Pract. 2010;60:611–615. - PMC - PubMed